Held · Bookmarked
0 · 0
portfolios · users
Avg position size
—
of holders' portfolios
13F filers
1
institution
Market cap
$77.4M
13M shares
52-week range
$3.25 – $13.50
30% from low
Sector
PHARMACEUTICAL PREPARATIONS
Exchange
NASDAQ
CS
Borrow rate
4.80%
Moderate
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| 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | |
|---|---|---|---|---|---|---|---|---|
| Revenue | $0 | $0 | $206.0K | $723.0K | $473.0K | $654.0K | $342.0K | $200.0K |
| Cost of revenue | $0 | $900.0K | $65.0K | $289.0K | $26.0K | $121.0K | $70.0K | $43.0K |
| Gross profit | $0 | −$900.0K | $141.0K | $434.0K | $447.0K | $533.0K | $272.0K | $157.0K |
| Gross margin | — | — | 68.4% | 60.0% | 94.5% | 81.5% | 79.5% | 78.5% |
| R&D | $6.6M | $8.8M | $15.2M | $28.4M | $31.9M | $26.7M | $20.1M | $14.0M |
| Operating income | −$323.9K | −$16.3M | −$20.2M | −$50.0M | −$48.4M | −$40.5M | −$33.1M | −$23.1M |
| EBITDA | −$8.5M | −$15.2M | −$17.0M | −$8.3M | −$25.6M | −$43.2M | −$33.7M | −$22.0M |
| Net income | −$277.3K | −$16.2M | −$19.3M | −$9.7M | −$29.9M | −$49.5M | −$39.4M | −$26.2M |
| Net margin | — | — | -9357.8% | -1347.2% | -6325.2% | -7569.4% | -11520.5% | -13086.5% |
| EPS (diluted) | -0.09 | -4.69 | -5.51 | -3.16 | -4.69 | -9.43 | -5.67 | -2.65 |
Annual figures · source: Financial Modeling Prep
| Year | Est. revenue | Est. EPS | EPS range | # Analysts |
|---|---|---|---|---|
| 2026 | $207400 | $-1.79 | $-1.90–$-1.67 | 3 |
| 2027 | $24M | $-1.47 | $-1.73–$-1.21 | 3 |
| 2028 | $166M | $2.11 | $-0.62–$5.89 | 5 |
| 2029 | $340M | $6.04 | $-1.65–$18.46 | 1 |
Forward consensus · source: Financial Modeling Prep
Clene Inc is a clinical-stage pharmaceutical company pioneering the discovery, development, and commercialization of novel clean-surfaced nanotechnology (CSN) therapeutics. It is focused on the development of therapeutics for neurodegenerative diseases. It developed an electro-crystal-chemistry drug development platform that enables the production of concentrated, stable, clean-surfaced nanocrystal suspensions. It operates in one segment the development and commercialization of dietary supplements (Supplements). Products includes CNM-Au8, CNM-ZnA, CNM-AgZn17, rMetx, KHC46.
www.clene.comNo one on the platform currently holds CLNN.
| Institution | Shares | Reported |
|---|---|---|
| Renaissance Technologiesas of 2025-09-30 | 30,440 | $183.4K |
| Execution date | Ratio |
|---|---|
| 2024-07-11 | 1-for-20reverse |
No one on the platform has traded CLNN yet.
| $309M |
| — |
| ORMPOramed Pharmaceuticals Inc. | $4.64 | -0.64% | $190M | — |
| OVIDOvid Therapeutics Inc. | $2.72 | +6.67% | $359M | — |
Source: Financial Modeling Prep · peers by sector/industry
Trading at 116.3× sales vs its 258.2× historical median P/S.
Fair value ≈ $14.07 · price $6.33 today
Fair-value line = the stock's median historical P/S × sales per share. Price below the orange line = cheap vs its own history; above = expensive. Not investment advice.
$CLNN CLENE says 10% reduction in Nfl levels led to 7% survival benefit How did they deduce that? Was this data statistically significant? For example, if a patient lives 15 instead of 14 months, that's 7% survival benefit. But how did clene estimate that the baseline is 14%? I hope it is not the case but it all sounds a massive amount of handwaving and cherry picking data points. Any kind of survival benefit is welcome news for the patients, but from the FDA's standpoint, how did clene perform the statistical analysis to come up with such numbers? Seems marginal, and contrived analysis. Hope to be wrong but clene will have a nearby impossible task to convince the FDA biostatisticians. $10 would 2x my investment, and I might half my position to play with only the house money. From these numbers I am not convinced CLENE has the data to warrant accelerated approval.
View on StockTwits ↗$CLNN Another new high profile ALS diagnosis revealed with former NFL star Chris Johnson announcing during an interview with Michael Strahan on GMA that he has ALS. So much attention now on this horrible disease and will be a lot of pressure on FDA to approve a new treatment or have a robust justification for another rejection. Given CNM Au8 is safe for all and perhaps the easiest drug to administer / take, even if it only helps some how can FDA possibly tells these patients sorry you have to wait another few years for a phase 3? I know it is not as simple as this but I do feel that the political climate has completely shifted in the past year and CLNN's chances are stronger than ever for AA.
View on StockTwits ↗$CLNN Just fyi FDA posted a video about clinical outcome vs surrogate endpoints for rare diseases, which is applicable for ALS as well. Understanding Endpoints in Rare Disease Drug Development https://www.youtube.com/watch?v=lHQ66qjXPoU
View on StockTwits ↗$CLNN 2/2 The abstracts from the two publications about Clene's posters below. https://www.aan.com/msa/Public/Events/AbstractDetails/65039 https://www.mdaconference.org/abstract-library/lb-igfbp7-as-a-nexus-biomarker-identifying-a-coordinated-treatment-response-phenotype-in-als-post-hoc-exploratory-analysis-from-regimen-c-of-the-healey/
View on StockTwits ↗$CLNN 1/2 Clene presented two posters at the ENCALS Meeting in Madrid last week. (I think this is the Linkedin post @Takeover24 wanted to share). https://www.linkedin.com/posts/clene-nanomedicine_encals-als-activity-7476276845445943296-QVG0 We were proud to have our Vice President of Medical Affairs, Marjan Sepassi, present two posters at the ENCALS Meeting in Madrid. The meeting brought together members of the global ALS community to share research, exchange insights, and advance conversations around improving care and outcomes for people living with ALS. We thank Marjan, our collaborators, and everyone who contributed to this work.
View on StockTwits ↗$CLNN https://www.linkedin.com/feed Continuing to establish the link between NFL decrease and survival!
View on StockTwits ↗$CLNN Looks like a cap, but it’s just low‑float biotech mechanics. Market makers and algos pin the price when liquidity is thin and positioning isn’t finished. These walls vanish the moment volume spikes or a real buyer steps in. Nothing fundamental changed — just tape games in a small name. Accumulating when I can.
View on StockTwits ↗@Mulhollandr - sounds good. I guess this is a forever hold type stock. Let ‘er run! $CLNN
View on StockTwits ↗@Mulhollandr - thanks for all of that…. Kinda thinking $CLNN gets bought out at some point after being derisked via acceptance. Hard to imagine what value would be placed on what could be a very exciting pipeline
View on StockTwits ↗$CLNN I fed info and asked Claude to challenge me over a lengthy exchange where I provided points and counter points to Claude’s pushback. Here is where we landed. (1) $CLNN bull case, comprehensively. Sub-$100M cap with NDA submission targeted Q3 2026 for CNM-Au8 in ALS under accelerated approval pathway (Subpart H). FDA’s final May 2026 meeting minutes confirmed the proposed data may support submission, with NfL serving as a reasonably likely surrogate endpoint. This wasn’t a one-meeting outcome — it’s the product of years of iterated FDA dialogue. Multiple Type C meetings, written guidance from DN1, FDA-recommended analyses pursued and delivered. The agency walked Clene through the gate. That dialogue pattern materially lowers the probability of an efficacy-driven CRL relative to base rate.
View on StockTwits ↗$CLNN short interest dropped just a touch to just over a million shares.
View on StockTwits ↗$CLNN just curious… is anyone on this board in the black with CLNN? sadly, i am not until it hits 17.06.
View on StockTwits ↗Recent $TICKER stream from stocktwits.com — refreshed every 5 minutes. Sentiment tags are self-reported by posters. Not investment advice.
Click to see transaction details on SEC.gov. Form 4s cover trades by officers, directors, and 10%+ owners, due within 2 business days of the trade.